Bone Mineral Density in Epileptic Children Getting Long Term Anti-epileptic Drugs

Background: Epilepsy is a common chronic neurological disorder with more than half of cases beginning in childhood. Most patients require long-term, and sometimes life-long, therapy antiepileptic drugs (AEDs). AEDs are associated significant side effects including radiological evidence rickets, decreased bone mineral density (BMD), altered turnover, increased risk fracture.
 Aim the Study: To assess epileptic children getting long term anti-epileptic drugs.
 Materials Methods: This study was conducted Saleh Child Development Disability Management Center (SCDDMC), Institute Mother Health (ICMH) Matuail, Dhaka. A total 31 childrens age ranged 5-15 years diagnosed as epilepsy on basis both clinical examination investigation (EEG) receiving (AEDS) for at least two were recruited this study.
 Results: Almost third (61.3%) group 5 to 10 12(38.7%) 15 years. Around three fourth (74.2%) male 8(25.8%) female. More (67.7%) had adequate sun exposure (77.4%) got calcium vit.D rich food. Majority (83.9%) phenobarbitone (PB) followed by 17(54.8%) combination, 13(41.9%) valproic acid (VPA), 11(35.5%) Nitrazipum (NTZ). one (38.7%) mono therapy, 19(61.3%) polytherapy. (96.8%) serum normal. The mean 9.22±0.78 mg/dl. BMD spine 0.66±0.14. neck left femur 0.66±0.15. right low (<-1SD) Z score. (60.0%) showed score normal (>-1SD) 6(28.6%) (<-1SD). (71.4%) poly 4(20.0%) No association found between type duration therapy.
 Conclusion: due use mono-therapy or assessment among essential.